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Misoprostol CAS:59122-46-2
Molecular Formula: C22H38O5
Molecular Weight: 382.60
Deleted CAS: 62015-39-8
Synonyms: Cytotec;Isprelor;Misogon;Misoprost;Misoprostil;SC 29333;
Density: 1.078 g/cm3
Boiling Point: 497.3 °C at 760 mmHg
Flash Point: 160.3 °C
Appearance: water-soluble, viscous liquid
Solubility: Soluble to 100 mM in Ethanol
Safety: Poison by ingestion, intramuscular, and intraperitoneal routes. When heated to decomposition it emits acrid smoke and irritating fumes.
PackAge: Aluminium foil bag packingÂ
Storage: Keep in cool and dry place, away from light
Use: Misoprostol is approved for use in the prevention of NSAID-induced gastric ulcers. It acts upon gastric parietal cells, inhibiting the secretion of gastric acid by G-protein coupled receptor-mediated inhibition of adenylate cyclase, which leads to decreased intracellular cyclic AMP levels and decreased proton pump activity at the apical surface of the parietal cell. Because other classes of drugs, especially H2-receptor antagonists and proton pump inhibitors, are more effective for the treatment of acute peptic ulcers, misoprostol is only indicated for use by people who are both taking NSAIDs and are at high risk for NSAID-induced ulcers, including the elderly and people with ulcer complications. Misoprostol is sometimes coprescribed with NSAIDs to prevent their common adverse effect of gastric ulceration (e.g. with diclofenac in Arthrotec).
Misoprostol has other protective actions, but is only clinically effective at doses high enough to reduce gastric acid secretion. For instance, at lower doses, misoprostol may stimulate increased secretion of the protective mucus that lines the gastrointestinal tract and increase mucosal blood flow, thereby increasing mucosal integrity. However, these effects are not pronounced enough to warrant prescription of misoprostol at doses lower than those needed to achieve gastric acid suppression.
However, even in the treatment of NSAID-induced ulcers, omeprazole proved to be at least as effective as misoprostol,but was significantly better tolerated, so misoprostol should not be considered a first-line treatment. Misoprostol-induced diarrhea and the need for multiple daily doses (typically four) are the main issues impairing compliance with therapy.
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---------------------  Additional Information  --------------------Â
Place of origin : China
Brand : YC
Certificate : ISO9001, KOSHER, GMP, SGS
Minimum order quantity : 5 Grams
Production capacity : 1000 Kilograms/Month
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----------------------  Delivery Information  ----------------------
Packing : Foil bag/tin or as your request
Payment : T/T, Western Union, MoneyGram
Port : Shanghai, Shenzhen, Hongkong
Shipment method : EMS, DHL, FeDex, UPS, etc
Leading  time : Within 24 hours after payment
Delivery time : safe & timely, around 4 days after payment.
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---------------------- Our Competitive Advantages  -------------------
1,Rich experience.
Our company is a professional production leading factory in China in pharmaceutical area of many years
2,Great quality, purity and favourable.
Our company is a professional leading factory in China in pharmaceutical area.Good quality is one of our secret success.
3,Safe and fast delivery.
We have stock, so we can delivery quickly at the very day when receive the payment.
4,Package: Professional packing with professional materials
5,Competitive Prices : Low price with high qulity
6,Good after-sales service : making all efforts to meet customers' need.
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Misoprostol CAS:59122-46-2
Molecular Formula: C22H38O5
Molecular Weight: 382.60
Deleted CAS: 62015-39-8
Synonyms: Cytotec;Isprelor;Misogon;Misoprost;Misoprostil;SC 29333;
Density: 1.078 g/cm3
Boiling Point: 497.3 °C at 760 mmHg
Flash Point: 160.3 °C
Appearance: water-soluble, viscous liquid
Solubility: Soluble to 100 mM in Ethanol
Safety: Poison by ingestion, intramuscular, and intraperitoneal routes. When heated to decomposition it emits acrid smoke and irritating fumes.
PackAge: Aluminium foil bag packingÂ
Storage: Keep in cool and dry place, away from light
Use: Misoprostol is approved for use in the prevention of NSAID-induced gastric ulcers. It acts upon gastric parietal cells, inhibiting the secretion of gastric acid by G-protein coupled receptor-mediated inhibition of adenylate cyclase, which leads to decreased intracellular cyclic AMP levels and decreased proton pump activity at the apical surface of the parietal cell. Because other classes of drugs, especially H2-receptor antagonists and proton pump inhibitors, are more effective for the treatment of acute peptic ulcers, misoprostol is only indicated for use by people who are both taking NSAIDs and are at high risk for NSAID-induced ulcers, including the elderly and people with ulcer complications. Misoprostol is sometimes coprescribed with NSAIDs to prevent their common adverse effect of gastric ulceration (e.g. with diclofenac in Arthrotec).
Misoprostol has other protective actions, but is only clinically effective at doses high enough to reduce gastric acid secretion. For instance, at lower doses, misoprostol may stimulate increased secretion of the protective mucus that lines the gastrointestinal tract and increase mucosal blood flow, thereby increasing mucosal integrity. However, these effects are not pronounced enough to warrant prescription of misoprostol at doses lower than those needed to achieve gastric acid suppression.
However, even in the treatment of NSAID-induced ulcers, omeprazole proved to be at least as effective as misoprostol,but was significantly better tolerated, so misoprostol should not be considered a first-line treatment. Misoprostol-induced diarrhea and the need for multiple daily doses (typically four) are the main issues impairing compliance with therapy.
Â
---------------------  Additional Information  --------------------Â
Place of origin : China
Brand : YC
Certificate : ISO9001, KOSHER, GMP, SGS
Minimum order quantity : 5 Grams
Production capacity : 1000 Kilograms/Month
Â
----------------------  Delivery Information  ----------------------
Packing : Foil bag/tin or as your request
Payment : T/T, Western Union, MoneyGram
Port : Shanghai, Shenzhen, Hongkong
Shipment method : EMS, DHL, FeDex, UPS, etc
Leading  time : Within 24 hours after payment
Delivery time : safe & timely, around 4 days after payment.
Â
---------------------- Our Competitive Advantages  -------------------
1,Rich experience.
Our company is a professional production leading factory in China in pharmaceutical area of many years
2,Great quality, purity and favourable.
Our company is a professional leading factory in China in pharmaceutical area.Good quality is one of our secret success.
3,Safe and fast delivery.
We have stock, so we can delivery quickly at the very day when receive the payment.
4,Package: Professional packing with professional materials
5,Competitive Prices : Low price with high qulity
6,Good after-sales service : making all efforts to meet customers' need.
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Model NO.: CAS: 59122-46-2
Flash Point: 160.3 °c
Trademark: YC
Transport Package: as Your Request
Specification: ISO9001 GMP KOSHER
Origin: China
Model NO.: CAS: 59122-46-2
Flash Point: 160.3 °c
Trademark: YC
Transport Package: as Your Request
Specification: ISO9001 GMP KOSHER
Origin: China